HUGIn is designed to explore chromatin organizations across multiple human cell lines and primary tissues. HUGIn incorporates data from multiple sources including genetic variants (SNPs), chromatin organization features (including topologically associating domain (TAD) boundaries, frequently interacting regions (FIRE)s, and long-range chromatin interactions from the analysis of Hi-C data) gene expression (from tissue or cell line specific RNA-Seq data), and multiple epigenetic datasets (including information on typical and super enhancers, CTCF binding sites, H3K4me1, H3K4me3, H3K27ac, H3K36me3, H3K27me3 and H3K9me3 peaks). Current data are all mapped to the reference genome hg19 (Genome Reference Consortium GRCh37). For more details and a complete tutorial, please see our
Tutorial page.